How common is MTHFR C677T mutation?
There are two common types, or variants, of MTHFR mutations: C677T and A1298C. These gene mutations are relatively common. In fact, in the United States, around 25% of people of Hispanic descent and 10–15% of people of Caucasian descent have two copies of C677T.
What does it mean to be heterozygous for MTHFR A1298C?
Some people have a genetic mutation in 1 or both of their MTHFR genes. People with a mutation in 1 MTHFR gene are are said to be heterozygous; if mutations are present in both genes, the person is said to be homozygous or compound heterozygous for the mutation(s).
What is A1298C heterozygous?
Heterozygous A1298C is thought to be of minor consequence (if any), while heterozygous C677T may affect folate metabolism by up to 35% (3, 11). MTHFR mutations that have the greatest influence on health are: Homozygous A1298C (C1298C) and homozygous C677T (T677T)
What is the c667t and A1298C gene mutation?
Some people are diagnosed with both the C667t and the A1298C gene mutations, simply put this means that they have a combination of the above problems which means that the right treatments are even more important.
How much will the gene mutation c667t affect my health?
How much the gene mutation C667T will affect your health, for example: The problems experienced by the C677T gene mutation are more likely to have elevated homocysteine. Cardiovascular disease, stroke, heart attack, and deep vein thrombosis. The family history of associated diseases is also common.
What is MTHFR gene mutation A1298C?
MTHFR Gene Mutation (A1298C) By the way for those that don’t know MTHFR stands for ( M ethylene T etra H ydro F olate R eductase) which is a regulatory enzyme (a catalyst) which is an extremely important folate (a nutrient) dependent, which is involved in literally hundreds of chemical reactions in the body that should keep us healthy.
What is the MTHFR C677T mutation?
All humans have certain genetic variations or “mutations” that can influence our health. One of the more well-studied variations is known as an MTHFR mutation; more specifically MTHFR C677T and A1298C.