What is a Kinevac study?

What is a Kinevac study?

Kinevac (Sincalide for Injection) may be used: (1) to stimulate gallbladder contraction, as may be assessed by various methods of diagnostic imaging, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals; (2) to stimulate pancreatic …

What is Kinevac used for?

Sincalide is used to help diagnose disorders of the gallbladder or pancreas. Sincalide is also used to speed up digestion of barium, a contrast agent, given in preparation for x-ray examination of the intestines. Sincalide may also be used for purposes not listed in this medication guide.

What is Kinevac injection?

Overview. KINEVACĀ® (sincalide for injection) is a cholecystopancreatic-gastrointestinal peptide hormone for parenteral administration that has a physiological effect on the gallbladder.

What is normal gallbladder ejection fraction?

Biliary dyskinesia, or hypokinesia of the gallbladder, is accepted as an ejection fraction less than 35%, while an accepted normal functioning gallbladder ejection fraction is greater than 35%.

What is a HIDA scan used for?

Gallbladder and bile duct A HIDA scan is most often done to evaluate your gallbladder. It’s also used to look at the bile-excreting function of your liver and to track the flow of bile from your liver into your small intestine. A HIDA scan is often used with X-ray and ultrasound.

How do you make Kinevac?

Kinevac: 30 minutes after initiation of secretin infusion, administer Kinevac 0.02 mcg/kg diluted in 30 mL of 0.9% Sodium Chloride Injection USP and infused over 30 minutes at a rate of 1 mL per minute.

What is J2805 used for?

HCPCS code J2805 for Injection, sincalide, 5 micrograms as maintained by CMS falls under Drugs, Administered by Injection .

Why is there a Kinevac shortage?

Reason for the Shortage Bracco Diagnostics had Kinevac injection on shortage due to manufacturing delays. There are no approved alternatives to sincalide injection for the labeled indications.

Who is the manufacturer of kinevac?

KINEVAC is manufactured for Bracco Diagnostics Inc., Monroe Township, NJ 08831, by Jubilant HollisterStier LLC, Spokane, WA 99207. KINEVAC is a registered trademark of Bracco Diagnostics Inc.

Is kinevac more stable when reconstituted with sterile water?

Kinevac reconstituted with 0.9% sodium chloride resulted in chemical stability of the injection, with 80.05% recovery of the time zero value after 8 h. Conclusion: Kinevac is more stable when reconstituted with sterile water than when reconstituted with 0.9% sodium chloride.

Is fatty meal-stimulated cholescintigraphy similar to kinevac?

We conclude that fatty-meal-stimulated cholescintigraphy is well tolerated and easy to perform and results in ejection fraction values similar to those obtained with Kinevac-stimulated cholescintigraphy. We are in the process of evaluating the clinical significance of the ejection fractions obtained with the fatty meal.