AdministratorWhat is the normal level for phenobarbital?
The therapeutic range for adults taking phenobarbital is 15-40 micrograms/milliliter (mcg/ml) (65-173 micromole/liter) for seizure treatment, and 5-15 micrograms/milliliter (mcg/ml) (22-65 micromole/liter) for sedative-hypnotic use.
What level controlled substance is phenobarbital?
The Drug Enforcement Administration (DEA) classifies phenobarbital as a Schedule IV controlled substance, signifying that it can result in the development of physical dependence when used for a significant length of time, and it is a potential drug of abuse.
When should a phenobarbital level be checked?
We will usually recommend checking a phenobarbital level 4 weeks after reaching a therapeutic dose and then every 4-12 months thereafter.
How much is too much phenobarbital?
Phenobarbital Overdose A lethal dose of phenobarbital is 6-10 grams, which a person may have in their medicine cabinet if they have been prescribed this drug. As a daytime sedative, a doctor may prescribe anywhere from 30 mg to 120 mg, and as an insomnia treatment, an individual could take as much as 320 mg.
What is the overdose of phenobarbital?
An overdose of phenobarbital can be fatal. Overdose symptoms may include slow or shallow breathing, weak pulse, cold or clammy skin, little or no urination, pinpoint pupils, feeling cold, or fainting. Drinking alcohol with this medicine can cause side effects. This medication may impair your thinking or reactions.
What is the pH of phenobarbital?
It contains a phenobarbital. Sodium phenobarbital is an odorless white crystalline powder. Aqueous solutions are alkaline to litmus and phenolphthalein (pH approximately 9.3).
What are the indications of phenobarbital?
Long-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the emergency control of certain acute convulsive episodes, e.g., those associated with status epilepticus, cholera, eclampsia, meningitis, tetanus, and toxic reactions to strychnine or local anesthetics.