What does salivary testosterone do?

What does salivary testosterone do?

Salivary testosterone (Sal-T) is believed to represent tissue hormone levels, which are unaffected by variations in circulating binding proteins (15), thereby providing an alternative to serum free testosterone (free-T) in the assessment of androgen status.

How accurate are saliva testosterone tests?

In conclusion, salivary testosterone does not accurately and reliably diagnose Low-T in men. Salivary testosterone is a good indicator of free testosterone. Free testosterone has been utilized as a diagnostic marker by the Endocrine Society Guidelines for the management and diagnosis of hypogonadism in men.

Is 600 a good testosterone level?

Testosterone levels above or below the normal range are considered by many to be out of balance. Moreover, some researchers suggest that the healthiest men have testosterone levels between 400-600 ng/dL.

What happens if low T is not treated?

A lack of testosterone can sometimes have long-term, serious effects on the body. In men with very low levels, the bones can become weak, potentially causing a condition called osteoporosis. Osteoporosis makes people considerably more prone to injury.

What is the salimetrics testosterone enzyme immunoassay kit?

The Salimetrics Testosterone Enzyme Immunoassay Kit is a competitive immunoassay specifically designed and validated for the quantitative measurement of salivary Testosterone. It is not intended for diagnostic use. It is intended only for research use in humans and some animals. Salimetrics has not validated this kit for serum or plasma samples.

Does salivary testosterone affect serum testosterone?

The remaining testosterone is bound to serum proteins whereas the majority of testosterone in saliva is not protein-bound. Salivary testosterone levels are unaffected by salivary flow rate. The serum-saliva correlation for testosterone is very high for males, but only modest for females.

Is testosterone bound or unbound in saliva?

In blood, only 1-10% of Testosterone is in its unbound or biologically active form. The remaining Testosterone is bound to serum proteins. Unbound Testosterone enters saliva via intracellular mechanisms, and in saliva the majority of Testosterone is not protein-bound. Salivary Testosterone levels are unaffected by salivary flow rate.