What is Cetrotide injection used for?

What is Cetrotide injection used for?

Cetrotide (cetrorelix) is a gonadotropin releasing hormone (GnRH) antagonist that temporarily delays ovulation. It is used to prevent eggs from being released too early and can help your provider be more successful during your egg retrieval procedure.

Where do you inject Cetrotide?

Cetrotide™ is injected subcutaneously—or into the fatty tissue under your skin. The primary sites for injection are your abdomen—2 inches on either side of the navel, and your upper, outer-thigh where the skin is loose. Wash your hands thoroughly and make sure that the surface you work on is clean.

What is cetrorelix acetate used for?

This medication is used by women having certain fertility treatments (controlled ovarian stimulation). Cetrorelix is usually used in combination with other hormones (FSH and hCG). It works by blocking the release of a certain hormone (luteinizing hormone).

How do you give cetrorelix injection?

Wash your hands and inject CETROLIX INJECTION 0.25ML under the skin of the belly as instructed by your doctor. If you experience lower stomach pain with nausea or vomiting, please consult a doctor immediately as these might be signs of ovarian hyper-stimulation syndrome (OHSS).

How many days do you take Cetrotide for IVF?

When the single 3mg dose is given, Cetrotide is supposed to give 4 days of suppression (no LH surge for 96 hours). If the patient needs more days of stimulation beyond the 96 hours, the daily 0.25mg Cetrotide injections are given until the stimulation is completed and HCG is given.

Does Cetrotide stop ovulation?

What is Cetrotide used for? Cetrotide is used to prevent premature ovulation (early release of eggs from the ovary). It is given to women having ovarian stimulation (fertility treatment where the ovaries are stimulated to produce more eggs). The medicine can only be obtained with a prescription.

How many follicles are good for IVF?

Follicles Needed for an IVF Cycle During IVF treatment, your doctor wants to stimulate your ovaries to mature several follicles. Anywhere between 8 and 15 follicles is considered an acceptable amount.

When do you start Cetrotide in IVF?

Cetrotide or Ganrelix would normally be started after 4-6 days after the start of the fertility medications. This shortens the number of days that a woman must take injections.

When should I take cetrorelix injection?

Cetrotide® (cetrorelix acetate for injection) 0.25 mg may be administered subcutaneously once daily during the early- to mid-follicular phase. Cetrotide® 0.25 mg is administered on either stimulation day 5 (morning or evening) or day 6 (morning) and continued daily until the day of hCG administration.

Does Cetrotide affect egg quality?

Conclusion. Reduction of the cetrorelix dose in the antagonist protocol was not associated with any significant difference either in the number of oocytes retrieved or in the pregnancy rate.

What happens if you miss a day of Cetrotide?

What should I do if I missed a dose? If you miss a dose of CETROTIDE do not double dose. Discuss with your doctor when you should receive your next dose. Check with your doctor if you have any questions about this.

Does Cetrotide help follicle growth?

GnRH antagonists (Orgalutran and Cetrotide) Their action is short-lived and daily injections are needed to maintain their effect. By using this medication, we can continue stimulating follicle growth while preventing ovulation before egg collection.

What is cetrorelix acetate injection?

Cetrotide®(cetrorelix acetate for injection) 0.25 mg is a sterile lyophilized powder intended for subcutaneous injection after reconstitution with Sterile Water for Injection, USP (pH 5-8), that comes supplied in a 1.0 mL pre-filled syringe.

How do you use a Cetrotide injection?

Cetrotide ® is for injection under the skin of the lower abdominal area, preferably around, but staying at least one inch away from the belly button. Choose a different injection site each day to minimize local irritation. Dissolve Cetrotide ® powder only with the water contained in the pre-filled syringe.

What are the contraindications for cetrorelix acetate?

Cetrotide® (cetrorelix acetate for injection) is contraindicated under the following conditions: Hypersensitivity to cetrorelix acetate, extrinsic peptide hormones or mannitol. Known hypersensitivity to GnRH or any other GnRH analogs. Known or suspected pregnancy, and lactation (see PRECAUTIONS).

What is the mechanism of action of cetrorelix?

Cetrorelix is a Gonadotropin Releasing Hormone Antagonist. The mechanism of action of cetrorelix is as a Gonadotropin Releasing Hormone Receptor Antagonist. The physiologic effect of cetrorelix is by means of Decreased GnRH Secretion.