What is cysteine sulfenic acid?

What is cysteine sulfenic acid?

As a posttranslational protein modification, cysteine sulfenic acid (Cys-SOH) is well established as an oxidative stress-induced mediator of enzyme function and redox signaling.

What is sulfenic acid in chemistry?

A sulfenic acid is an organosulfur compound and oxoacid with the general formula RSOH. It is the first member of the family of organosulfur oxoacids, which also include sulfinic acids and sulfonic acids, RSO2H and RSO3H, respectively. The base member of the sulfenic acid series with R = H is hydrogen thioperoxide.

What is the formula of sulphonic acid?

A sulfonic acid (or sulphonic acid) refers to a member of the class of organosulfur compounds with the general formula R−S(=O)2−OH, where R is an organic alkyl or aryl group and the S(=O)2(OH) group a sulfonyl hydroxide.

How do you make sulfenic acid?

Sulfenic acids are produced by the reactions of a thiol with two-electron oxidants [3,94–97]. They can alternatively be generated via the hydrolysis of sulfenyl-halides, sulfenyl-thiocyanate [19,29,98–100] or thiosulfinate esters [82,83,101,102], or in radical-mediated reactions (see the later sections).

Is sulfenic acid an organic compound?

sulfonic acid, sulfonic also spelled sulphonic, any of a class of organic acids containing sulfur and having the general formula RSO3H, in which R is an organic combining group.

What is the use of sulfenic acid?

Sulfenic acids, formed as transient intermediates during the reaction of cysteine residues with peroxides, play significant roles in enzyme catalysis and regulation, and are also involved in the redox regulation of transcription factors and other signaling proteins.

What will be formed if cysteine undergoes oxidation reaction?

Thiol groups in protein cysteine (Cys) residues can undergo one- and two-electron oxidation reactions leading to the formation of thiyl radicals or sulfenic acids, respectively.

What is the purpose of sulphonic acid?

Sulphonic acid is an organic acid, which is very important in liquid detergent production. It neutralizes the basic effect of sodium hydroxide (Caustic soda): It is one of the foaming agents for liquid detergent.

What is amino sulfonic acid used for?

The sulfonic acids are among the most important of the organosulfur compounds; the free acids are widely used as catalysts in organic syntheses, while the salts and other derivatives form the basis of the manufacture of detergents, water-soluble dyes and catalysts, sulfonamide pharmaceuticals, and ion-exchange resins.

Is sulfenic acid present in onion?

When you cut into an onion, you break open loads of individual onion cells. These ruptured cells release special enzymes as well as amino acid sulfoxides, which form sulfenic acid. The sulfenic acid in onion enzymes react to form Syn-Propanethial S-Oxide.

How do you make phenylsulfinic acid?

Phenylsulfinic acid can be prepared in several ways, most easily through reduction of sulfonyl chlorides with zinc dust or iron. However other starting materials can be used. Due to the air sensitivity of this compound it is often formed as a salt.

What is the main use of phenylsulfinic acid?

The main use of phenylsulfinic acid is for the asymmetric synthesis of carbon-carbon bonds due to its ability to stabilize negative charges on an adjacent carbon atom. Phenylsulfinic acid has been a component for electroplating of palladium alloys.

What happens when phenylsulfinic acid reacts with sulfur?

When phenylsulfinic acid reacts with sulfur to give thiosulfinates and thiosulfinic acids. The main use of phenylsulfinic acid is for the asymmetric synthesis of carbon-carbon bonds due to its ability to stabilize negative charges on an adjacent carbon atom.

What is the p Ka of phenylsulfinic acid?

There is a large range of p Ka values in the literature, with most authors giving a value of around 1. 30. This inconsistency can be explained by differences in ionic strength between quoted values. By measuring the p Ka at various ionic strengths and extrapolating to zero ionic strength, the p Ka of phenylsulfinic acid was determined to be 2. 76.