What is immunohematology test?

What is immunohematology test?

Immunohematological tests enable safe blood transfusion and transplantation of haematopoietic tissue, as well as prevent undesired immune-related phenomena after transfusion, transplantation and during pregnancy.

What are RBC Alloantibodies?

In blood banking, an antibody formed in response to pregnancy, transfusion, or transplantation targeted against a blood group antigen that is not present on the person’s red blood cells.

What is Dolichos Biflorus used for?

The Dolichos biflorus is a well known medicinal plant in folklore for its medicinal properties. In herbal medicine the seeds of it are mainly used as tonic, astringent, diuretic, and are also recommended in asthma, bronchitis, urinary discharges, hiccoughs, ozoena, heart trouble and other diseases of brain.

What is another name for the immunohematology department?

The blood bank is the department where blood is stored and prepared for transfusion. It is also known as the Immunohematology department because most of the testing involves antigens and antibodies (immunology) found on the RBCs (hematology).

What are the common aspects of immunohematology?

At the heart of immunohematology is detecting these antigens on red blood cells (RBCs) and the corresponding antibodies individuals may produce….Immunohaematology

  • Platelet.
  • Hematocrit.
  • Transfusion Medicine.
  • Dithiothreitol.
  • Nuclear Protein.
  • Autoantibodies.
  • Phenotype.
  • Blood Group Antigen.

What have you learned about immunohematology?

Immunohaematology studies the reactions that take place between antigens present on blood cells and antibodies present in plasma. Patients undergoing transfusion therapy are tested for their ABO and RhD blood groups and the presence of any antibodies that may cause a reaction between their plasma and donor red cells.

What antibodies are Alloantibodies?

Alloantibodies are immune antibodies that are only produced following exposure to foreign red blood cell antigens.

  • Produced by exposure to foreign red cell antigens which are non-self antigens but are of the same species.
  • They react only with allogenic cells.
  • Exposure occurs through pregnancy or transfusion.

What does a positive autocontrol mean?

When a patient has an autoantibody, the direct antiglobulin test and the autocontrol in an antibody panel will be positive. In addition, all cells in the panel will be reactive. If the antibody reactions are stronger at colder temperatures and weaker at warm temperatures, the patient probably has a cold autoantibody.

What is Dolichos Biflorus?

Dolichos biflorus agglutinin (DBA) is isolated from horse gram. Dolichos biflorus agglutinin is a glycoprotein with a molecular weight of about 111 kDa and consists of 4 subunits of approximately equal size. This lectin has a carbohydrate specificity toward α-linked N-acetylgalactosamine.

What’s the difference between the A1 and A2 antigen?

A1 and A2 are distinguished by the reactivity of lectin i.e., anti-A1 which occurs as a cold agglutinin and exclusively agglutinates A1 cells. About 0.4% A2 and 25% of A2B subgroups possess anti-A1. These antibodies become clinically significant if they react at 37°C destroying A1 cells [2].