What is the cortical substance of the kidney?
The renal cortex (cortical substance; substantia corticalis) is reddish brown in color and soft and granular in consistence. It lies immediately beneath the fibrous tunic, arches over the bases of the pyramids, and dips in between adjacent pyramids toward the renal sinus.
What does renal cortical mean?
noun, plural: renal cortexes or renal cortices. The outer region of the kidney where the glomeruli, the proximal convoluted tubules, and the distal convoluted tubules are located. Supplement. The kidney is the organ responsible for filtering blood and producing urine.
What are HRCE cells?
Human Renal Epithelial Cells (HRE) are comprised of cells from the cortex and glomerular region. Human Renal Cortical Cells (HRCE) are from proximal and distal tubules. Human Mesangial Cells (HMC) are isolated from the renal glomerulus and modified smooth muscle cells between capillaries.
What is the function of cortex in the kidney?
The cortex provides a space for arterioles and venules from the renal artery and vein, as well as the glomerular capillaries, to perfuse the nephrons of the kidney. Erythropotein, a hormone necessary for the synthesis of new red blood cells, is also produced in the renal cortex.
What causes cortical thinning in kidney?
This type of kidney atrophy is due to a lower blood supply to the kidney(s)and/or loss of nephrons, the basic working units of the kidneys. Chronic infections or blockage of the kidney can also result in kidney atrophy. A kidney that is smaller in size can lead to kidney disease.
What is the cortex and medulla of the kidney?
renal medulla: The inner-most region of the kidney, arranged into pyramid-like structures, that consists of the bulk of nephron structure. renal cortex: The outer region of the kidney, between the renal capsule and the renal medulla, that consists of a space that contains blood vessels that connect to the nephrons.
What causes thinning of kidney cortex?
What causes kidney atrophy? Kidney atrophy may be due to: Blocked kidney artery (known as renal artery stenosis) – blocks the main arteries that supply blood to the kidneys, which can be due to hardening of the arteries with fatty deposits or blood clots.
What causes thinning of the renal cortex?
What is the difference between renal cortex and renal medulla?
The main difference between renal cortex and renal medulla is that renal cortex is the outer region of the kidney which contains blood vessels connected to the nephrons whereas renal medulla is the inner region of the kidney which contains 8-12 renal pyramids.
Can cortical thinning be reversed?
After weight gain, this cortical thinning can be reversed to a normal level15,16,17. Cortical thinning seems to be confined to the somatosensory cortex, the cingulo-parietal network, and the occipital cortex8,13,18,19,20.